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1.
Open Dentistry Journal ; 15(1):300-304, 2021.
Article in English | EMBASE | ID: covidwho-1334852

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)is a virus responsible for the coronavirus infection that is currently causing a severe outbreak of the disease in the world, infecting and killing thousands to lacs of people. The pediatric and geriatric population is no exception to this. Children and older adults have less immunity, which makes them more susceptible to infection than other populations. But still the number of cases of Children where less as compared to adults and those having underlying pulmonary pathology or immunocompromising conditions are more vulnerable to infection. Some studies have shown that this virus causes more death in the older age population as compared to adults or children. Patients having any systemic conditions like diabetes, raised blood pressure, heart diseases, lung diseases and chronic renal diseases were more vulnerable to this infection. In this article, we will outline the epidemiology, symptoms, diagnosis, and treatment modalities of the novel coronavirus-2019(COVID 19) infection in humans, with more focusing on infection in children as well as in older adults.

2.
Open Dentistry Journal ; 15(1):296-299, 2021.
Article in English | EMBASE | ID: covidwho-1334851

ABSTRACT

To date, the 21st century has encountered various outbreaks, causing global disruption and highlighting our vulnerability to epidemics. Coronavirus disease (COVID-19) is a highly infectious respiratory illness. Approximately 15% of the affected individuals show severe symptoms requiring oxygen, and of these, 5% require ventilation. This pandemic has affected more than 216 countries or territories (by 20th September 2020), infecting more than 30.6 million people;hitherto, 950000 deaths have been reported. This public health emergency has created a disproportionate burden on the health care system worldwide. Therefore, the management and resolution of this critical situations require the mobilisation of excessive human resources for rapid response, and time is essential in the management of this crisis. Together, these factors contribute to the rapid capacity development with the minimal investment of time and resources, which requires the deployment of an existing skilled workforce, such as public health dentists. These dentists have administrative capabilities and can work in coherence with the community and other health professionals. The present review aims to highlight the areas in which the untapped potential of Public Health Dentists can be explored to tackle the COVID-19 pandemic.

3.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1593-1598, 2020.
Article in English | EMBASE | ID: covidwho-1077042

ABSTRACT

The novel coronavirus has disrupted the normal life of each individual with masks becoming an integral part of life. Mostly every person is well informed about the precautions that need to be taken for the containment of the virus such as regular hand washing, wearing of masks in outdoors, social distancing, etc. Yet there has been little reference to the deleterious habit of smoking that can weigh heavily on one’s health. This article aims to look into the connec-tion and intricacies of smoking that may directly or indirectly affect the severity of the symptoms of COVID-19. Smoking is already a known etiologic factor for many cardiovascular and pulmonary diseases such as Chronic Obstructive Pulmonary Disease (COPD), coronary artery disease, carcinoma of the lungs, etc. While COVID-19 is a virus that causes respiratory distress in severe cases, not much is known or emphasized in the medical field of its possible relationship with smoking. Our information is limited to whether the presence of smoking history in infected patients worsens the condition or there is no relationship between smoking and COVID-19. Moreover, with the introduction of lockdown as a measure to contain the virus, it substantially increases the incidence of anxiety, depression and other mental health diseases which can contribute tremendously to the relapses of smoking or convert a non-smoker to a smoker. Hence, it is imperative to look into the possible relationship of Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2) and smok-ing.

4.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1500-1506, 2020.
Article in English | EMBASE | ID: covidwho-1044531

ABSTRACT

The whole world is under the grip of a pandemic of COVID-19, a disease caused by a newly discovered strain of coronavirus and the name given is SARS-CoV2. The term ’novel’ is used for this virus because researches suggest that its origin is from an animal which was transmitted to a human and now is capable of having transmission from human to human. Symptoms of COVID-19 can be mild to severe. Mortality is high in severe cases. Also, this virus is a serious threat to the elderly and people with other systemic illness. There is no specific protocol provided for its treatment and the treatment primarily focuses on symptomatic relief. Human immune systems have never come across this particular type of strain of virus before. As a result, human body has not developed immunity for it moreover no effective vaccine is developed for it at this point of time. But there is an active strenuous work going on to understand more and more about the interaction of host-pathogen, how does host immunity responses to this virus moreover how this pathogen is able to invade the immune system which can be utilised for the development of a vaccine. As the disease is highly infectious, there is an urgent need for the development of a vaccine. Hence this review aims to summarize the undergoing scientific work and research in progress for the development of vaccine and all the advancement that has come in focus for its development.

5.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1447-1451, 2020.
Article in English | EMBASE | ID: covidwho-1044180

ABSTRACT

Coronavirus is a rapidly emerging infectious disease of respiratory tract which has been declared a pandemic by World health Organization. The virus spread quickly between close contacts or thought coughing and sneezing of the infected person. A few months after the first case was reported in Wuhan, China, the disease quickly turned into a pandemic. World health experts are already actively searching for a cure or vaccine for this disease, but before that, many countries around the world are considering mass quarantine measures as a method to combat its spread. This necessitates application of strict measures to control this pandemic. As of now there is no treatment to cure this disease. Therefore prevention of spread of disease remains the mainstay of combating it. One of the emergency public health measures that have been used extensively to control this pandemic is quarantine. Even though on long term basis, quarantine may have its advantages and disadvantages which has to be considered when practicing the same. This review focuses on rational behind the quarantine, its indications, the set-up or infrastructure required and the ethical implication for quarantine. It also reviews the psychological impact of quarantine and its effectiveness as a public health measure.

6.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1517-1523, 2020.
Article in English | EMBASE | ID: covidwho-1043743

ABSTRACT

Coronavirus disease 2019 had caused a pandemic leading to over 6M posi-tive cases worldwide out of which 3.73 lac are demised (until when the article was written). Its first outbreak was seen in Wuhan, China. In the Indian sce-nario, we have a total of 2 lac cases out of which 5,679 have been deceased (until when the article was written). Due to the high transmissibility of this disease, the entire country is under lockdown to prevent the spread of the virus. The main etiology of this virus is the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2). This affects the respiratory system leading to cough, shortness of breath, and fever. There have been cases with mild or no symptoms reported, but the cause of death is due to the virus. This helps us understand the diagnosis, epidemiology, symptoms, and pathophysiology about the virus, which can help in treatment modalities. An autopsy is one of the methods by which we can understand the systematic involvement other than the respiratory system. Various pathological, microbiological changes can occur in the other organs. Even though the person is deceased, the virus is highly infectious can cause the spread through body fluids. Proper care must be taken while handling the body and performing the procedure. This review article aims to focus on the autopsy findings found in various cases to study the disease pathophysiology of the SARS-CoV-2. This article also helps us understand the guidelines that have been put forward by WHO and CDC must be followed regarding the specification required in the autopsy room;PPE’s to be worn, human waste and fluid disposal, body transportation. Proper per-sonal hygiene must be maintained while handling the COVID-19 patients;this can lead to less susceptibility of acquiring the disease.

7.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1599-1604, 2020.
Article in English | EMBASE | ID: covidwho-1042618

ABSTRACT

The most recent severe acute respiratory condition corona infection outburst has overwhelmed an ill-equipped nature among a festival season. It was first appeared on December 1, 2019, Wuhan (China) and recognized as a coron-avirus and has spread worldwide. The manifestations are fever, discomfort and cough which resolve in a couple of days yet may advance to an extreme in most of the cases, but if any comorbidity exists in the form of diabetes, hypertension or any other debilitating systemic disease, then it can lead to grave prognosis. It spread mainly from one person to another through air droplet. Although no vaccines have been discovered yet but still scientists are working relentlessly to find one. Thus, the society has must think about the complementary and alternative medicinal system. India has its traditional medicine “AYUSH”, which comprises of Ayurveda, Yoga, Unani, Siddha, and Homeopathy. This review mainly aims to summarize the point’s alternative to allopathy. AYUSH helps in immune system boosting, act as an antiviral, anti-inflammatory, stress release. It has been reported in the literature that it has no side effect and is safe to use. So this current situation provides an opportunity to employ ancient traditional medicine to take part and try to deal in the best way to withstand covid-19.

8.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1452-1457, 2020.
Article in English | EMBASE | ID: covidwho-1042250

ABSTRACT

The pandemic of coronavirus infection 2019 (COVID-19) started from Wuhan, China, in December a year ago and has become a significant test to general wellbeing China as well as nations around the globe. Affecting the population of 4,735,622 in the world and leads to the death of 316,289 till 19th May 2020, according to reports of WHO. The COVID-19 spread rapidly by a human to human contact through small droplets from mouth and nose. Other possible routes of transmission for COVID-19, include airborne spread via aerosols produces during dental procedures. The dentists are at higher risk of getting infected by coronavirus disease with many routine dental procedures hav-ing the possibility to transmit the virus through aerosols. During the time of COVID-19 pandemic disease, the health care workers should be provided with protective apparatus including face shields, goggles, mask, gloves, gown or coverall, headcover and rubber boots. American Dental Association has maintained a consistency neutral stance since the pandemic was recognized. They appealed dental health care workers to put off elective dental procedures for dental patients and to provide only urgent dental care. Essential phone screening to distinguish suspected patients or likely COVID-19 contaminated can be correctly done during routine dental arrangements. This review high-lights on the structure of coronavirus, its modes of communication, how dental health care workers are at higher risk, urgent dental procedures that should only begin during the crisis and basis preventive measures taken by dental health care workers.

9.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1469-1472, 2020.
Article in English | EMBASE | ID: covidwho-1042045

ABSTRACT

The Coronavirus Disease 2019 started in Wuhan Province, China and which spread to half a dozen countries between 2019 and 2020 and was declared a pandemic. This resulted in the implementation of a lockdown in different parts of the world, explaining it was an effective and essential way to break the cycle of infection. Physical distancing is the most important measure to break this infection cycle which affected many people’s lives in different aspects. Mental health is considered to be one of the important components of the overall health as the definition given by the World Health Organization. It says that the person should be well-adjusted with the environment and should not be easily upset. He should know his needs, problems and goals properly;moreover, if he faces problems, he tries to solve them intelligently for which he tries to cope up with stress and anxiety. Along with all these things, he has good self-control balances between rationality and emotionality. It has likewise set off a wide variety of mental issues, for example, anxiety, panic disorder and depression. Most of the studies have reported negative impacts, including anger, stress symptoms and confusion. Education and training on pandemic should be provided by the authorities and health care workers.

10.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1473-1476, 2020.
Article in English | EMBASE | ID: covidwho-1041677

ABSTRACT

The COVID 19 outbreak has been declared a pandemic by the world health organisation. The healthcare sector was overburdened and overstretched with the number of patient increasing and requiring health services. The worst-hit population always are the people with special needs, whether it is children, pregnant females or the geriatric population. The need for the emergency kind of health services was so inflated that the other special population which required them equally as those patients with the COVID 19 suffered a lot. Dentistry was not an exception, and even that is also one of the important components of the health care delivery system and people requiring oral health care needs were also more. Those undergoing dental treatments would not have completed the treatment, and this would have resulted in various complications. In this situation, some dental emergency guidelines have been released by Centres for Disease Control (CDC) for the urgent dental care those requiring special care dentistry during the COVID 19 pandemic. Children with special care needs were considered more vulnerable to oral diseases;hence priority should have been given to them for dental treatments moreover in the future also more aggressive preventive measures should be taken in order to maintain oral hygiene and prevent many oral diseases. Guardians/caregivers should be made aware and motivated to maintain the oral health of children with special health care needs. This review mainly focuses on the prevention and management of oral diseases in children’s with special care needs.

11.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1529-1533, 2020.
Article in English | EMBASE | ID: covidwho-1041523

ABSTRACT

The SARS-CoV-2 is a novel coronavirus which originated in the province Wuhan, China, in December 2019. It is the causative agent of COVID-19, an infection mainly presenting as mild upper respiratory tract infection, with patients presenting with fever, cough, breathlessness and fatigue. The virus predominantly spreads by a person to person contact, which is why it has spread very rapidly in a short span of time, so much so, that multiple countries are affected at present. The number of casualties is ever increasing. Even though our understanding of the novel coronavirus is improving, many countries, including India, are facing a situation which is not getting better with respect to controlling the pandemic. The number of new cases and deaths are ever increasing. There is a general state of panic among all the sections of the society and almost all are affected. With the number of tests being carried out every day, also increasing, a general idea about the signs and symptoms of the disease as well as the diagnostic criterion aids will further help us control the pandemic. This narrative review focuses on the clinical symptoms, diagnostic aids, risk factors, common clinical symptoms, laboratory findings and complications of COVID-19 and also on post COVID 19 Complications.

12.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):1319-1322, 2020.
Article in English | EMBASE | ID: covidwho-995073

ABSTRACT

Myths are like wildfire, spreading across the globe in no time. How can this elude the scenario of a pandemic? The COVID-19 pandemics brought several misconceptions under its hood in 2020. No doubt, the major base of the myth was based on virtual and social media platforms. Twitter, Facebook, What-sapp were exploited to share the myths amongst the crowd for a long time. A massive chunk of the various data in context to the origin, spread and transmission of the virus was found unreliable from these sources. These were later found to be of a great impact on the mental health of the individuals. It was hence essential to create an official portal that gave the correct insight to the Pandemic and also guides individuals regarding their protection and prevention of the disease. This review has been made with an attempt to through light on some myths prevailing about the COVID-19 Pandemic and to bust them under the appropriate facts. Attempts have been made to separate facts from the fiction. In the latter half, various official organisations working in relief against the Pandemic have been discussed for the ease of identification.

13.
International Journal of Current Research and Review ; 12(19):82-87, 2020.
Article in English | Scopus | ID: covidwho-859381

ABSTRACT

The rapid spread of novel corona virus declared as a pandemic by the World Health Organisation has created a sense of panic across the globe, nor sparing the Dentistry in the process. The mode of transmission of the virus is through infected secretions such as saliva and respiratory secretions or their respiratory droplets, which are expelled when an infected person coughs, sneezes, talks or sings, has created the need to control the contact spread of the infectious virus between humans. This de-manded a responsible emergence of medical as well as Dental care to handle the situation of the pandemic with utmost care. The need for proper guidelines from time to time has been a key to the emerging safe dental practices amongst dental profes-sionals. Focusing not only on the emergencies but also on the routine procedures is a major challenge at the present. The best delivery of dental treatment can only be given when proper protocols are being followed. A crucial aspect being the protection of the spread of the disease from an asymptomatic patient should be considered. This review has been articulated considering the dire need of the hour to protect the dental professionals, the auxiliaries as well as the patient from the infectious spread of the disease. It encourages them to know the various methods of the protective aspects of dentistry amidst this pandemic and its importance in clinical practice. Also, additional aspects of precautions while screening the patient, while performing various procedures and the disinfection of the operatory has been discussed. © IJCRR.

14.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):420-424, 2020.
Article in English | Scopus | ID: covidwho-830417

ABSTRACT

Covid-19 is an outbreak of a severe acute respiratory disorder which emerged in December 2019 in Wuhan, China. Since then the virus has spread to many countries and has become and pandemic. The mortality rate of the disease is very high but it varies from country to country depending on the medical facilities and the observance of isolation among the population. As the disease is very contagious many different treatment modalities have been tried. The therapeutic methods which are used are Ayurvedic and homeopathic along with that some Allopathic drugs are also used. Ayurvedic and home-opathy were found to be useful in asymptomatic patients rather than symp-tomatic patients. The drug which is used for treatment is antiviral drugs, pro-tease inhibitors, antimalarial drugs, and neuraminidase inhibitors. But most promising results were obtained by using hydroxychloroquine, thus many countries are using this drug for treatment. Research related to vaccine development is still in progress. but there is still an absence of data regarding the effectiveness of these methods. Clinical trials need to be performed to prove the drug or the measure effective. While the search for a vaccine is still under-way, preventive measures should be taken to curb the chain of infection. This includes the use of face mask, washing hands frequently, at least 1meter dis-tance while in public places. This Literature review summarizes all the measures that have been used for the treatment of COVID 19 pandemic all around the world. © International Journal of Research in Pharmaceutical Sciences.

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